Goodpasture Syndrome Overview

Goodpasture syndrome is a rare and life-threatening autoimmune condition that can affect the lungs and kidneys. When the immune system functions properly, antibodies work to fight off germs and infections. Goodpasture syndrome is a perplexing disorder that represents the opposite effect, whereas the immune system creates antibodies that actually attack the lungs and kidneys. People with Goodpasture syndrome will typically have a shortness of breath and feel fatigue; more severe symptoms will follow such as coughing up blood, extreme difficulty in urinating and blood in the urine. In some cases, a dangerous build-up of blood can occur in the lungs. There are many complicated factors involved in testing for the kidney disorder as well as treating it and among some is a genetic factor. Goodpasture syndrome can now be diagnosed with a special blood test, and in some cases, through a kidney biopsy. Treatment is available using immunosuppressive drugs and for some the disorder can be cured in a matter of a few weeks, while for others, it can last for up to two years.

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